Courses > Semester 1

Biology I

Lesson Contents

  • Properties and origin of life
  • Chemical Structure of life (The chemistry of Carbon and the organic molecules, Chemistry of water, Biological macromolecules).
  • The Prokaryotes: Bacteria and Archaea.
  • Viruses and their pathogenic effects, viroids and prions
  • Organisation of Eukaryotic cell (biomembranes, cell wall, cell communication, cytoskeletal structures, cellular organelles, cell division and cell cycle regulation)
  • Genetics (laws of heredity, chromosomes and Mendel/s Genetics, mode of action and interaction of genes, mutations, population genetics and molecular nature of the genetic material of cells)

Laboratory exercises

  1. Morphology of Eukaryotes. Microscopic observation of single cell eukaryotic organisms.
  2. Staining and microscopic observation of the cell nucleus in plant and animal cells.
  3. Microscopic observation of procaryotic cells (Bacteria and Archaea)
  4. Bacterial nutrition. Prokaryotic cell cultures under aseptic conditions in the laboratory. Developing Prokaryotic cells from natural sources.
  5. Culture of Prokaryotic cells on solid substrates. Determination of the number of bacterial cells developed from soil material.
  6. The prokaryotic cells grown on solid substrates and give colonies. Determination of the number of bacterial cells developed from soil material. Assessment and evaluation of results.
  7. Cell fractionation of eukaryotic cells by differential centrifugation. Isolation of nuclear and mitochondrial fraction of hepatocytes extract.
  8. Isolation of DNA from epithelial cells of the oral cavity.

Educational Books

Theory

  • Biology, E. Zifa, Z. Mamuris, K.A. Moutou, University of Thessaly Press, 2008 (in Greek)
  • Biology, N.A. Campbell & J.B. Reece, 8th edition, Pearson Benjamin Cummings, 2007.
  • Biology, P.H. Raven, G.B. Johnston, J.B. Losos, K.A. Mason & S.R. Singer 8th ed., McGraw-Hill, 2008.
  • Life, The Science of Biology, W.K. Purves, D.Sadava, G.Orians & C. Heller, 7th edition, Sinauer Associates, 2003.
  • Molecular Biology of the Cell, B. Alberts et. al., 5th edition, Garland Science

Laboratory

  • Laboratory Exercises in Biology, K. Vareli, I. Sainis and Th. Traga, University of Ioannina Press.

Inorganic Chemistry

Theory:

The laws of Chemistry (Lavoisier, Proust, Dalton, etc), atomic models and structure, the four quantum numbers, atomic orbitals, periodic table, principles of filling orbitals with electrons, chemical bonding (covalent, ionic, hydrogen bonding, etc), conductors, insulators, semiconductors, molecular orbitals theory for simple diatomic molecules, molecular geometry, hybridization, small molecules geometry prediction by VESPR (Valence shell electron pair repulsion) principles, coordination chemistry, structure of coordination compounds, solutions and solutes solubility, concentration expressions, ideal-non ideal solutions, Raoult law, azeotropic mixtures, osmotic pressure, ionic compounds solutions, solubility product constants (Ksp), ionic equilibria, pH determination of weak acid and bases, hydrolysis, indicators, acid-base titrations, Redox chemistry, galvanic cells.

Laboratory:

Laboratory practice includes

  1. Safety in a chemical lab
  2. Mg atomic weight determination
  3. Alkaline earth metal ions - halogens properties
  4. Oxidation-Reduction. Simple displacement reactions
  5. The Le Chatelier principle
  6. Anions-cations hydrolysis. pH estimation using indicators
  7. Acid-base titrations
  8. Glycine titration. Determination of the ionization constants and isoelectric point
  9. Spectroscopic determination of chemical equilibria constants.
  10. Reaction kinetics. Rate constants and activation energy determinations
  11. Redox chemistry. Galvanic cells

Mathematics

Course contents:

Functions. Infinite Sequences and Series. Limits of functions and continuity. Calculus of exponential, logarithmic, trigonometric functions and applications. Derivatives and applications. Iintegrals, integration techniques and applications of integration. Difference and differential equations. Introduction to mathematical modeling.

Introduction to Informatics

Course Outline

  • Computers and Informatics
  • Hardware and Peripheral Units
  • Computer Systems
  • Data Processing
  • Information Storage
  • Operating Systems
  • Computer Networks and Data Communications
  • Internet and Internet Technologies
  • Computer Graphics
  • Multimedia
  • Computer Algorithms
  • Software Programming
  • Programming Languages
  • Software systems
  • Information Systems

Laboratory Exercises

  • Working with Windows
  • Word Processing
  • Spreadsheets
  • Designing and Managing Databases
  • Designing and Creating Presentations
  • Internet Applications
  • Working with Unix
  • Developing Computer Programs

Organic Chemistry I: Hydrocarbons and derivatives

  1. Hydrocarbons (alkanes, alkenes, alkines, dienes and polyenes, cycloalkanes)
  2. Conformers, Newman projections, Nomenclature, Haloganation of alkanes through free radical mechanism)
  3. Addition reaction to a C=C double bond. Geometrical isomers (cis/trans; E/Z)
  4. Acids and bases in the organic chemistry
  5. Cycloalkanes (stability, Bayer strain, boat and chair conformations of cyclohexane
  6. Hydrocarbon derivatives (alcohols, ethers, amines, alkyl halides, mercaptanes). Nucleophilic aliphatic substitution (mechanisms SN1 and SN2)
  7. Stereochemistry, Optical isomers (enantiomers, diastereomers)
  8. Basic concepts: acidity, basicity, inductive and mesomeric effect, Resonance, Tautomerism, Nuclophilicity, Electrophilicity
  9. Oxidative-reductive reactions
  10. Aromatic compounds, aromaticity, nomenclature, electrophilic aromatic substitution (chlorination, nitration, sulfuration, Friedel-Carfts alkylation and acylation), nucleophilic aromatic substitution (Meisenheimer complex, benzyne intermediate), polycyclic aromatic hydrocarbons

Physics

Geometrical Optics: reflection, refraction, mirrors, lenses, optical instruments (camera, magnifying lens, microscope) Wave Optics: interference, diffraction, time and space coherence, optical grating, spectrometer

Elements of Quatum Mechanics: wave-particle behaviour of matter, electronic microscope, uncertainty principle, wavefunction, quantum probability, tunneling effect, quantization of energy

Elements of Atomic physics: atomic orbitals, quantization of angular momentum, atomic states and energies for hydrogen, hydrogenic ions, multielectron atoms and ions, Pauli’s exclusion principle, Periodic Table, atomic transitions and spectra, nuclear magnetic resonance (NMR), electron spin resonance (ESR)

Elements of Molecular Physics: molecular orbitals and molecular states, electronic, vibrational and rotational energies, diatomic and polyatomic molecules, radiative molecular transitions and molecular spectra x-rays: production, diffraction from matter, emission and absorption spectra

Elements of matter structure: types of binding in solids, cohesion forces

Elements of Nuclear Physics: structure and size of nuclei, isotopes, mass deficiency, nuclear forces, radioactivity, radiodating, biological effects of ionizing radiation, medical applications, nuclear reactions, fission, nuclear reactors, fusion